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3.

Pearson correlation coefficients between the expression of TMEM88 and the genes involved in the Wnt signal pathway in TCGA.

Gene symbol Description P Pearson χ2
DVL1 Dishevelled segment
polarity protein 1
< 0.001 0.206
DVL2 Dishevelled segment
polarity protein 2
< 0.050 0.102
DVL3 Dishevelled segment
polarity protein 3
< 0.050 –0.107
FZD10 Frizzled class receptor 10 < 0.050 –0.101
FZD2 Frizzled class receptor 2 < 0.010 0.139
FZD4 Frizzled class receptor 4 < 0.001 0.266
FZD5 Frizzled class receptor 5 < 0.001 0.390
FZD7 Frizzled class receptor 7 < 0.050 –0.124
FZD8 Frizzled class receptor 8 < 0.010 0.138
ROR1 Receptor tyrosine kinase like orphan receptor 1 < 0.001 0.301
WNT5A Wnt family member 5A < 0.010 –0.155