Figure 2.

Effect of different subthalamic nucleus (STN) quadripolar stimulating electrode configurations on HFS‐induced suppression of the striatal tonically active neuron (TAN) spike rate. Peri‐stimulus time histogram (PSTH; bin width of 0.5 s) recorded from same TAN neuron. The stimulation lasted 30 s. The tonic firing rate of striatal TANs was suppressed during STN‐HFS using all three quadripolar configurations without significant differences (P > 0.05, Kruskal–Wallis test). Red bars indicate the stimulation period. HFS: high‐frequency stimulation; (+): anodes; (−): cathodes. The location of the stimulation contact is described in Fig. 1. [Colour figure can be viewed at wileyonlinelibrary.com].