Table 5.
Association of AURKA genotype frequencies with laboratory findings in liver tests from HCC patients.
| Characteristic | α-Fetoprotein a (ng/mL) | AST (IU/L) | ALT (IU/L) | AST/ALT ratio |
|---|---|---|---|---|
| rs1047972 | ||||
| CC | 1226.8 ± 365.6 | 58.61 ± 5.88 | 54.82 ± 5.48 | 1.23 ± 0.03 |
| TC+TT | 396.8 ± 153.0 | 47.51 ± 3.91 | 49.10 ± 4.84 | 1.19 ± 0.04 |
| p value | 0.037* | 0.116 | 0.434 | 0.470 |
| rs2273535 | ||||
| TT | 1480.6 ± 523.4 | 63.39 ± 8.66 | 57.91 ± 8.00 | 1.23 ± 0.03 |
| AT+AA | 601.2 ± 230.3 | 48.89 ± 3.41 | 49.20 ± 3.63 | 1.21 ± 0.05 |
| p value | 0.125 | 0.120 | 0.322 | 0.654 |
| rs2064863 | ||||
| TT | 1144.4 ± 369.3 | 57.82 ± 6.18 | 54.39 ± 5.77 | 1.22 ± 0.02 |
| GT+GG | 772.8 ± 380.2 | 51.79 ± 5.12 | 51.36 ± 5.25 | 1.21 ± 0.07 |
| p value | 0.483 | 0.453 | 0.698 | 0.889 |
| rs6024836 | ||||
| AA | 1365.9 ± 493.4 | 65.00 ± 9.21 | 59.93 ± 8.49 | 1.26 ± 0.05 |
| AG+GG | 753.0 ± 314.7 | 48.41 ± 3.35 | 48.01 ± 3.57 | 1.19 ± 0.02 |
| p value | 0.295 | 0.091 | 0.196 | 0.193 |
Mann-Whitney U test was used between two groups.
a Mean ± S.E.
* p value < 0.05 as statistically significant.