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. 2018 Jan 1;15(1):36–45. doi: 10.7150/ijms.21666

Table 1.

Clinical trials using hESC-RPE and iPSC-derived cells

hESC-RPE cellular therapy iPSC-derived cells in clinical trials
Condition ClinicalTrials.gov Identifier number/ Phase/ Status Condition ClinicalTrials.gov Identifier number/ Source/ Status
Age Related Macular Degeneration, Stargardt's Disease, Exudative Age-related, Macular Degeneration NCT02903576/ I/II/ study is currently recruiting participants Leukemia, Lymphoma
NCT02564484/ blood/ study is currently recruiting participants
Dry Age Related Macular Degeneration NCT01344993/ I/II/ study has been completed Ataxia-Telangiectasia (A-T) NCT02246491/ blood, skin/ study is currently recruiting participants
Stargardt's Macular Dystrophy NCT01345006/ I/II/ study has been completed Chronic Granulomatous Disease
NCT02926963/ hair, skin/ study is currently recruiting participants
Dry Age-related Macular Degeneration NCT03046407/ early 1/ study is currently recruiting participants Retinoblastoma
NCT02193724/ skin, blood/ study is currently recruiting participants
Stargardt's Macular Dystrophy NCT01469832/ I/II/ study has been completed Autism Spectrum Disorder NCT02720939/ blood/ study is currently recruiting participants
Dry Macular Degeneration,
Geographic Atrophy
NCT02590692/ I/II/ study is currently recruiting participants Ectodermal Dysplasia
NCT02896387/ skin, cornea/ study is currently recruiting participants
Dry Age-related Macular Degeneration NCT02755428/ early 1/ study is currently recruiting participants Intellectual Deficiency, Asymptomatic Carrier of the Mutation of the Gene MYT1L, Healthy Volunteers
Macular Degeneration,
Stargardt's Macular Dystrophy
NCT02749734/ I/ study is currently recruiting participants NCT02980302/ skin/ study is currently recruiting participants
Age-related Macular Degeneration NCT02286089/ I/II/ study is currently recruiting participants
Age-related Macular Degeneration NCT03102138/ I/ study is currently recruiting participants