Table 1.

Main characteristics of the cell lines.

Cell line	Site of origin	Pathology	Molecular type (6)	Triple negative subtype (7)	BRCA1 status	TP53 status
MCF10A	Normal breast	Fibrocystic	Basal B	-	Wild type	Wild Type
MCF7	Pleural effusion	Adenocarcinoma	Luminal	-	Wild type	Wild Type
T47D	Pleural effusion	Adenocarcinoma	Luminal	-	Wild type	Missense mutation
MDA231	Pleural effusion	Adenocarcinoma	Basal B	MSL	Wild type	Missense mutation
MDA436	Pleural effusion	Adenocarcinoma	Basal B	MSL	5382insC	Nonsense mutation
HCC1937	Primary tumor	Infiltrating ductal carcinoma	Basal A	BL1	5396 + 1G>A	Nonsense mutation
SUM149	Primary tumor	Inflammatory breast carcinoma	Basal B	BL2	2288delT	Missense mutation
SUM1315	Skin metastasis	Infiltarting ductal carcinoma	Basal B	-	185delAG	Missense mutation
SUM1315-LXSN (SL)	Skin metastasis	Infiltarting ductal carcinoma	Basal B	-	185delAG	Missense mutation
SUM1315-BRCA1 (SB)	Skin metastasis	Infiltarting ductal carcinoma	Basal B	-	185delAG + sauvage	Missense mutation