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. Author manuscript; available in PMC: 2018 Jan 12.
Published in final edited form as: Free Radic Biol Med. 2016 Jun 3;97:212–222. doi: 10.1016/j.freeradbiomed.2016.06.002

Fig. 5.

Fig. 5

Lineage restricted deletion of gp91phox in myeloid cells inhibits Nf1+/− neointima formation. Representative photomicrographs (A) and quantification of neointima area (B and C) of injured carotid arteries from WT, Nf1flox/+;LysMcre, and Nf1flox/+;gp91flox/flox;LysMcre mice. A. Black arrows indicate neointima boundaries. Black boxes identify area of injured artery that is magnified below. Scale bars: 100 μm. B and C. Quantification of neointima area (B) and I/M ratio (C) of injured carotid arteries from WT, Nf1flox/+;LysMcre, and Nf1flox/+;gp91flox/flox;LysMcre mice. Data represent mean neointima area or I/M ratio±SEM, n=10–12. *P<0.001 for WT, and Nf1flox/+;gp91flox/flox;LysMcre mice versus Nf1flox/+;LysMcre.