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. 2018 Jan 9;11:61–75. doi: 10.2147/IDR.S148602

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© 2018 Gokarn and Pal. This work is published and licensed by Dove Medical Press Limited

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Susceptibility of metallo-β-lactamase-producing Acinetobacter baumannii to siderophores and antibiotics.

Notes: A. baumannii isolates were swabbed on the surface of MHA plates and antibiotic discs were placed. Then, either Exo-MS or DFO-B (10 μL each) were loaded onto the antibiotic discs. The antibiotics used were Amp, IMP, and MRP. On each plate, a different isolate was seeded. Zones of inhibition were observed with the siderophore+antibiotic combinations, indicating synergism. For example, in the second row, the left plate showed no zones of inhibition with ampicillin and siderophores individually. The siderophore+ampicillin combination showed zones of inhibition. Exo-MS and DFO-B individually showed no zones of inhibition.

Abbreviations: Amp, ampicillin; DFO-B, deferoxamine-B; Exo-MS, exochelin-MS; IMP, imipenem; MHA, Mueller–Hinton agar; MRP, meropenem.