Table 2.
MIC of Exo-MS for MRSA and MBL-producing Pseudomonas aeruginosa and Acinetobacter baumannii
| Isolates | Number of isolates inhibited at Exo-MS (mg/mL)
|
Total isolates inhibited (%) | Number of isolates inhibited at Exo-MS (mg/mL) + ampicillin 0.01 mg/mL
|
Total isolates inhibited (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0.05 | 0.125 | 0.25 | 0.5 | 0.05 | 0.125 | 0.25 | 0.5 | |||
| MRSA (n=20) | 4 | 6 | 2 | 1 | 13 (65) | 6 | 6 | 2 | 1 | 15 (75) |
| MBL-producing P. aeruginosa (n=15) | 0 | 3 | 0 | 0 | 3 (20) | 1 | 3 | 0 | 0 | 4 (27) |
| MBL-producing A. baumannii (n=15) | 1 | 2 | 2 | 0 | 5 (33) | 3 | 2 | 2 | 0 | 7 (47) |
Notes: MIC was determined by adding Exo-MS at different concentrations with or without ampicillin at 0.01 mg/mL. The number of isolates inhibited at the end of 24 h at 37°C are shown. n = total number of isolates of each pathogen. Medium control showed no growth, whereas growth control, ampicillin control, and “Fe” control showed growth (data not shown).
Abbreviations: Exo-MS, exochelin-MS; MBL, metallo-β-lactamase; MIC, minimum inhibitory concentration; MRSA, methicillin-resistant Staphylococcus aureus.