Table 1.
Retrospective studies comparing radical/WLE and radical vulvectomy
| Study | Stages | Number of patients | Results |
|---|---|---|---|
| Farias-Eisner68 | T1–2, N0–1 | 74 | 5-year OS – 97% vs 100% stage 1 95% vs 75% stage 2, P>0.05 Serious complications – 11% vs 25% |
| Balat et al38 | 49 | 5 years OS – 75% vs 67% LC 83% vs 80%, complications less in WLE |
|
| De Hullu et al69 | 238 | LR – 11.4% vs 7.5%, P=0.32 | |
| Rutledge et al39 | T1–2, N0 | 179 | Equal survival |
| De Simone et al40 | T1–2, N0 | 122 | LR – 13% vs 85 P=0.33, lymphedema – 7.5% vs 26%, P=−0.007, wound separation – 7.5% vs 23% |
Abbreviations: LC, local control; LR, likelihood ratio; OS, overall survival; WLE, wide local excision.