FPLC chromatograms of recovered Qβ samples subjected to shear rates of (A) 0.1 s−1, (B) 1 s−1, (C) 10 s−1, and (D) 50 s−1. DLS plots of recovered Qβ samples subjected to shear rates of (E) 0.1 s−1, (F) 1 s−1, (G) 10 s−1, and (H) 50 s−1. Both FPLC and DLS results indicate that low shear rates, from 0.1 to 1 s−1, resulted in an increase in aggregated species. Higher shear rates, up to 10 s−1, dispersed aggregated species due to the higher shear forces applied. Shear rates exceeding 10 s−1 induced particle breakup as evidenced by the appearance of a large peak at 22.5 mL on the FPLC chromatogram.