. Author manuscript; available in PMC: 2019 Jan 1.

Published in final edited form as: IEEE Trans Med Imaging. 2017 Jul 11;37(1):151–161. doi: 10.1109/TMI.2017.2725443

TABLE I.

Location-specific features and systemic information used in this study.

Local	Basic Clinical Measures (F1–F21)	Plaque composition: Plaque phenotype, DC/NC/FF/FT [CSA], DC/NC/FF/FT [%], max. confluent NC, max. NC angle, # NC abutting. Plaque morphology: Lumen/EEM/PM [CSA], PB, remodeling index, distance to ostium, mean plaque thickness, std. plaque thickness, eccentricity.
	First-Order Descriptors (F22–F30)	Plaque grayscale intensity: mean, median, std., max, min, mode. Plaque intensity histogram: first, median, third quartiles.
	Plaque Textures (F31–F46)	Contrast, correlation, energy, homogeneity [θ = 0°, 45°, 90°, 135°].
	Layered Plaque Components (F47–F118)	DC/NC/FF/FT [%] in 10%~90% inner & outer rings.
	Spatial Contextual Features (F119–F236)	Average feature value of one adjacent distal and one adjacent proximal frames. Calculate for all F1~F118.
Systemic	Demographics & Biomarkers (F237–F254)	Age, gender, weight, BMI, family history, smoking history, current smoker, hypertension, diabetes, hyperlipidemia, pervious MI, beta-blockers, ACE inhibitors, previous statin treatment, total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides.

DC: dense calcium; NC: necrotic core; FF: fibrofatty; FT: fibrotic tissue; BMI: body mass index; MI: myocardial infarction; ACE: angiotensin-converting enzyme; LDL: low-density lipoprotein; HDL: high-density lipoprotein.