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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Semin Arthritis Rheum. 2017 Feb 10;47(1):133–142. doi: 10.1016/j.semarthrit.2017.02.003

Table 2.

Covariates assessed in CIRT at baseline and/or during follow-up period.

Category Covariates
Sociodemographic

  • Age

  • Sex

  • Body mass index

  • Race/Ethnicity

  • Geography

  • Occupational history
Clinical

  • Prior history of cardiovascular disease:

    • Myocardial infarction, cerebrovascular accident, percutaneous coronary intervention, coronary artery bypass graft, other arterial vascularization, deep vein thrombosis, pulmonary embolism, atrial fibrillation, heart failure, hypertension, peripheral arterial disease, carotid disease, aortic stenosis, aortic or mitral valve procedure, mitral regurgitation

  • Co-morbid illness/Medical History

    • Hypertension, metabolic syndrome, diabetes mellitus (types 1 and 2), peripheral neuropathy, sleep apnea, asthma, hematologic disease (anemia, thrombocytopenia, neutropenia), non-alcoholic steatohepatitis, history of treated malignancy >5 years ago, macular degeneration, dialysis or offered kidney transplant, laser treatment or vitrectomy for diabetic eye disease, gestational diabetes

  • Medications

  • Physical exam: Heart rate, Blood pressure, Ankle-Brachial Index, recent Ejection Fraction

  • Symptoms (nausea, vomiting, diarrhea, mouth pains/sores, cough, shortness of breath, fever)

  • Smoking:

    • >100 cigarettes in lifetime

    • Age started smoking regularly

    • Years of smoking

    • Current smoking status

    • Cigarettes/day

    • Pack-years

  • Physical activity

  • Average alcohol consumption (number of drinks)

  • Caffeinated beverage consumption

  • Family history of myocardial infarction, cerebrovascular accident, diabetes mellitus
Laboratory and Imaging Studies

  • Hepatitis B and C

  • Safety panel: ALT, AST, Cr, Albumin, CBC, glucose

  • Lipids and hsCRP (fasting)

  • HbA1c

  • Urine testing

  • Chest x-ray (past 12 months)

  • Echocardiogram (past 3 years)

  • EKG

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; CBC, complete blood count, Cr, creatinine; EKG, electrocardiogram; HbA1c, hemoglobin A1c; hsCRP, high sensitivity C-reactive protein.