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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Glia. 2017 Aug 30;65(12):1990–2002. doi: 10.1002/glia.23209

Table 1.

Mouse strains used in this study

Genotype Description Abbreviation Reference
B6.Cg-Tg(Plp1-Cre/ERT)3Pop/J Tamoxifen Inducible Cre recombinase under the transcriptional control of the mOL marker Plp1 PlpCreER Doerflinger et al., 2003
FR-HrasG12V Mutant HRasG12V allele upstream of WT HRas flanked by loxP sites HRasG12V Chen et al., 2009
RBP-Jflox Endogenous rbpj gene flanked by loxP sites Rbpjflox Han et al., 2002
B6.Cg-Tg(Plp1-Cre/ERT)3Pop/J; FR-HrasG12V Tamoxifen administration mediates excision of endogenous (WT) HRas and expression of the mutant HRasG12V allele. pRsG/+ or pRsG/G --
B6.Cg-Tg(Plp1-Cre/ERT)3Pop/J; FR-HrasG12V;RBP-Jflox Tamoxifen administration mediates excision of endogenous (WT) HRas, expression of the mutant HRasG12V allele and inactivation of Rbpj. pRsG/+;pRbpj --