Table 2. Sample characteristics.
| Variable | N | Mean | SD |
|---|---|---|---|
| Age | 599 | 63.6 | 8.8 |
| Disease duration (years) | 599 | 3.6 | 2 |
| Sex (female) | 353 | ||
| Alignment | 599 | ||
| Varus | 228 | 38.7% | |
| Valgus | 184 | 31.2% | |
| K&L score | 599 | ||
| 1 | 8% | ||
| 2 | 48.4% | ||
| 3 | 40.4% | ||
| 4 | 3% | ||
| Laxity | 529 | ||
| No laxity | 60.3% | ||
| Mild | 34.4% | ||
| Moderate/severe | 5.3% | ||
| Worse pain previous week | 592 | 3 | 2.8 |
| WOMAC synovitis/effusion | |||
| Serum Comp (ng/mL) | 599 | 786.6 | 318.7 |
| Serum HA (ng/mL) | 599 | 67.9 | 64.6 |
| Urine NTXI (nmol BCE) | 599 | 253.2 | 192.0 |
| Urine CTXII (ug/L) | 599 | 2.6 | 2.3 |
| Urine CTX-1a (ng/mL) | 599 | 3.6 | 2.4 |
| Urine CTX-1ß (ug/L) | 599 | 17.4 | 15.8 |
| BMI (kg.m-2) | 597 | 30.7 | 4.8 |
| Blood pressure: systolic (mm Hg) | 597 | 124.6 | 15.3 |
| Blood pressure: diastolic (mm Hg) | 597 | 75.47 | 9.5 |
| CES-D | 592 | 6.82 | 6.8 |
| Widespread pain | 597 | 1.8 | 1.7 |
| Quadriceps Strength | 563 | 324.5 | 126.9 |
| WOMAC physical function | 599 | 9.5 | 11.3 |
| WOMAC pain | 599 | 3 | 3.5 |
BMI: body mass index
CES-D: Center for Epidemiologic Studies Depression scale
uNTXI: Urine N-Terminal Telopeptide type I
uCTXII: C-Terminal Telopeptide type II
uCTX-1ß: C-Terminal Telopeptide type 1ß
uCTX-1α: C-Terminal Telopeptide type 1α
sComp: Serum Cartilage Oligomeric Matrix Protein
sHA: Serum Hyaluronic Acid
nM BCE: nanomoles bone collagen equivalents