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. 2017 Aug 1;45(16):9797–9808. doi: 10.1093/nar/gkx698

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — (A) Scheme of the simplest theoretical form of an RNA hybridization network, a chain reaction. (B) Sequence-structure schematics of a designer chain reaction (system trigR2). The toehold sequence for the interaction between the two sRNAs (SR and SRR) is shown in blue, and the toehold sequence for the interaction between the heterodimer (sRNA complex) and the 5′ UTR (SRRR) is shown in red. In the 5′ UTR, the RBS (shown in yellow) functions as a kind of toehold to interact with the ribosome.