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. 2018 Jan 12;13(1):e0191307. doi: 10.1371/journal.pone.0191307

Table 1. Most abundant canine salivary proteins and their functions.

Protein name Gene name Total normalized spectral counts Function [reference]
Fc fragment of IgG binding protein FCGBP 797 Binds to IgG on mucosal surfaces [43]
Polymeric immunoglobulin receptor (precursor) PIGR 571 Transports IgA across epithelial cells [44]
BPI fold-containing family A member 2 BPIFA2 466 Key components of the innate immune response against Gram-negative bacteria [45]
BPI fold-containing family B member 1 isoform X2 BPIFB1 352 Key components of the innate immune response against Gram-negative bacteria [45]
Albumin ALB 296 Serum-derived protein believed to passively enter saliva. Saliva-specific functions include binding to hydroxyapatite and lubrication of oral tissues [46]
Ovostatin homolog 2-like LOC611455 270 GO: serine-type endopeptidase inhibitor activity
Mucin 19 MUC19 264 Gel-forming mucin that lubricates saliva and plays a role in reducing adherence and increasing clearance of bacteria [47]
Angiopoietin-related protein 5-like LOC607055 261 Not reported
Actin gamma 1 ACTG1 244 Cytoskeletal protein with multiple functions in the defense against intracellular pathogens [48]
Ig lambda chain V-I region BL2 LOC607368 219 Component of immunoglobulin light chains