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. Author manuscript; available in PMC: 2019 Jan 15.
Published in final edited form as: Virology. 2017 Nov 9;514:1–8. doi: 10.1016/j.virol.2017.10.020

Fig. 1.

Fig. 1

Five conserved RNA structures in HIV-1 genome. (A) Locations of the structures in HIV-1 genome. Three elements correspond to conserved structures encoding the junctions of polyprotein domains: MA and CA (A1), PR and RT (A2), RT and IN (A3). Two structures contain extended base-pairings are located in the regions encoding CA (B1) and nef (B2). (B) Nucleotide sequence and the predicted structures of the five RNA structures in the NL4-3 molecular clone. Nucleotides shown in red are replaced by synonymous mutations in mutant constructs.