Skip to main content
. Author manuscript; available in PMC: 2019 Jan 15.
Published in final edited form as: Eur J Pharmacol. 2017 Dec 10;819:261–269. doi: 10.1016/j.ejphar.2017.12.017

Figure 3.

Figure 3

Bladder Pressure during Voiding Induced by IV, SC and IM Administration of LMN-NKA.

Values are the mean + S.D. bladder voiding pressure after LMN-NKA from 2–12 rats per group. Note that voiding pressure did not increase with increasing doses of LMN-NKA. This indicates that voiding pressure is set by intrinsic properties of the urethra in acute spinal animals and that LMN-NKA was not influencing urethral resistance. (No voiding occurred with saline vehicle and vehicle bars represent the baseline pressures at 70% bladder capacity) One-way ANOVA: F(3,24) = 68.02, for IV; F(5,41) = 21.19, for SC; F(6,48) = 6.39, for IM, all P<0.0001. *P<0.05 compared with vehicle baseline pressure, Dunnett’s multiple comparison tests.