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. 2018 Jan 12;8:670. doi: 10.1038/s41598-017-18428-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Lymph Node and Lung Micro-Metastases. (a) Representative MDA-MB-231 metastatic cells in lung section immunostained for CK18. (b) A group of normal respiratory epithelial cells showing weak immunostaining for CD18. (c) Representative metastasis (labeled “M”) in lymph node section immunostained for CD18. Black wedges mark endothelial cells in mammary gland ducts surrounding lymph nodes.