Table 4.
Aligned the sequences of ZIKV Env p1, p6, p7, p8, p14, p29, p31, p32, p38, p41 and p42 against those of DENV 1–4, WNV and YFV.
| Peptide name | Peptide Sequence | Sequence Identity |
|---|---|---|
| Peptide 1 variants | ||
| ZIKV P1 | IRCIGVSNRDFVEGMSGGTW | |
| WNV P1 | FNCLGMSNRDFLEGVSGATW | 13/20 |
| YFV P1 | AHCIGITDRDFIEGVHGGTW | 12/20 |
| DENV1 P1 | MRCVGIGNRDFVEGLSGATW | 14/20 |
| DENV2 P1 | MRCIGISNRDFVEGVSGGSW | 16/20 |
| DENV3 P1 | MRCVGVGNRDFVEGLSGATW | 15/20 |
| DENV4 P1 | MRCVGVGNRDFVEGVSGGAW | 15/20 |
| Peptide 6 variants | ||
| ZIKV P6 | SNMAEVRSYCYEASISDMAS | |
| WNV P6 | ANLAEVRSYCYLATVSDLST | 12/20 |
| YFV P6 | DGPAEARKVCYSAVLTNVKI | 6/20 |
| DENV1 P6 | TNPAVLRKLCIEAKISNTTT | 8/20 |
| DENV2 P6 | KQPATLRKYCIEAKLTNTTT | 6/20 |
| DENV3 P6 | TQLATLRKLCIEGKITNITT | 5/20 |
| DENV4 P6 | KEVALLRTYCIEALISNITT | 8/20 |
| Peptide 7 variants | ||
| ZIKV P7 | YEASISDMASDSRCPTQGEA | |
| WNV P7 | YLATVSDLSTKAACPTMGEA | 10/20 |
| YFV P7 | YSAVLTNVKINDKCPSTGEA | 7/20 |
| DENV1 P7 | IEAKISNTTTDSRCPTQGEA | 14/20 |
| DENV2 P7 | IEAKLTNTTTESRCPTQGEP | 10/20 |
| DENV3 P7 | IEGKITNITTDSRCPTQGEA | 12/20 |
| DENV4 P7 | IEALISNITTATRCPTQGEP | 11/20 |
| Peptide 8 variants | ||
| ZIKV P8 | DSRCPTQGEAYLDKQSDTQY | |
| WNV P8 | KAACPTMGEAHNDKRADPAF | 9/20 |
| YFV P8 | NDKCPSTGEAHLEEENEGDN | 6/20 |
| DENV1 P8 | DSRCPTQGEATLVEEQDANF | 12/20 |
| DENV2 P8 | ESRCPTQGEPSLNEEQDKRF | 10/20 |
| DENV3 P8 | DSRCPTQGEAVLPEEQDQNY | 13/20 |
| DENV4 P8 | ATRCPTQGEPYLKEEQDQQY | 12/20 |
| Peptide 14 variants | ||
| ZIKV P14 | QPENLEYRIMLSVHGSQHSG | |
| WNV P14 | LKENIKYEVAIFVHGPTTVE | 6/20 |
| YFV P14 | DQTKIQYVIRAQLHVGAKQE | 3/20 |
| DENV1 P14 | QYENLKYSVIVTVHTGDQHQ | 7/20 |
| DENV2 P14 | QPENLEYTIVITPHSGEEHA | 9/20 |
| DENV3 P14 | QYENLKYTVIITVHTGDQHQ | 7/20 |
| DENV4 P14 | QIENLEYTVVVTVHNGDTHA | 8/20 |
| Peptide 25 variants | ||
| ZIKV P25 | ALVEFKDAHAKRQTVVVLGS | |
| WNV P25 | TLMEFEEPHATKQSVIALGS | 10/20 |
| YFV P25 | HLVEFEPPHAATIKVLALGN | 9/20 |
| DENV1 P25 | LLVTFKTAHAKKQEVVVLGS | 15/20 |
| DENV2 P25 | TLVTFKNPHAKKQDVVVLGS | 14/20 |
| DENV3 P25 | LLVTFKNAHAKKQEVVVLGS | 15/20 |
| DENV4 P25 | RMVTFKVPHAKRQDVTVLGS | 13/20 |
| Peptide 29 variants | ||
| ZIKV P29 | KGRLSSGHLKCRLKMDKLRL | |
| WNV P29 | TVKLTSGHLKCRVKMEKLQL | 13/20 |
| YFV P29 | LYKLHGGHVACRVKLSALTL | 8/20 |
| DENV1 P29 | TTTIFAGHLKCRLKMDKLTL | 13/20 |
| DENV2 P29 | GNLLFTGHLKCRLRMDKLQL | 13/20 |
| DENV3 P29 | GTSIFAGHLKCRLKMDKLEL | 13/20 |
| DENV4 P29 | GNHMFAGHLKCKVRMEKLRI | 7/20 |
| Peptide 31 variants | ||
| ZIKV P31 | KGVSYSLCTAAFTFTKIPAE | |
| WNV P31 | KGTTYGVCSKAFKFLGTPAD | 9/20 |
| YFV P31 | KGTSYKMCTDKMSFVKNPTD | 9/20 |
| DENV1 P31 | KGMSYVMCTGSFKLEKEVAE | 10/20 |
| DENV2 P31 | KGMSYSMCTGKFKVVKEIAE | 11/20 |
| DENV3 P31 | KGMSYAMCTNTFVLKKEVSE | 9/20 |
| DENV4 P31 | KGMSYTMCSGKFSIDKEMAE | 9/20 |
| Peptide 32 variants | ||
| ZIKV P32 | AFTFTKIPAETLHGTVTVEV | |
| WNV P32 | AFKFLGTPADTGHGTVVLEL | 11/20 |
| YFV P32 | KMSFVKNPTDTGHGTAVMQV | 8/20 |
| DENV1 P32 | SFKLEKEVAETQHGTVLVQV | 11/20 |
| DENV2 P32 | KFKVVKEIAETQHGTIVIRV | 9/20 |
| DENV3 P32 | TFVLKKEVSETQHGTILIKV | 8/20 |
| DENV4 P32 | KFSIDKEMAETQHGTTVVKV | 10/20 |
| Peptide 38 variants | ||
| ZIKV P38 | NSKMMLELDPPFGDSYIVIG | |
| WNV P38 | NAKVLIELEPPFGDSYIVVG | 14/20 |
| YFV P38 | DDEVLIEVNPPFGDSYIIVG | 11/20 |
| DENV1 P38 | EKPVNIETEPPFGESYIVVG | 10/20 |
| DENV2 P38 | DSPVNIEAEPPFGDSYIIVG | 11/20 |
| DENV3 P38 | DEPVNIEAEPPFGESNIVIG | 10/20 |
| DENV4 P38 | NSVTNIELEPPFGDSYIVIG | 15/20 |
| Peptide 41 variants | ||
| ZIKV P41 | HRSGSTIGKAFEATVRGAKR | |
| WNV P41 | HKSGSSIGKAFTTTLKGAQR | 13/20 |
| YFV P41 | HKEGSSIGKLFTQTMKGAER | 11/20 |
| DENV1 P41 | FKKGSSIGKMFEATARGARR | 13/20 |
| DENV2 P41 | FKKGSSIGQMFETTMRGAKR | 12/20 |
| DENV3 P41 | YKKGSSIGKMFEATARGARR | 13/20 |
| DENV4 P41 | FRKGSSIGKMFESTYRGAKR | 14/20 |
| Peptide 42 variants | ||
| ZIKV P42 | FEATVRGAKRMAVLGDTAWD | |
| WNV P42 | FTTTLKGAQRLAALGDTAWD | 13/20 |
| YFV P42 | FTQTMKGAERLAVMGDAAWD | 12/20 |
| DENV1 P42 | FEATARGARRMAILGDTAWD | 17/20 |
| DENV2 P42 | FETTMRGAKRMAILGDTAWD | 17/20 |
| DENV3 P42 | FEATARGARRMAILGDTAWD | 17/20 |
| DENV4 P42 | FESTYRGAKRMAILGETAWD | 16/20 |