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. 2018 Jan 12;8:692. doi: 10.1038/s41598-017-19040-z

Table 1.

COMT SNPs (single nucleotide polymorphisms) on suicidal phenotypes. Single marker association analyses (SNPs: rs4633, rs4680, rs737865, rs6269, rs165599). Significant p-values in bold. False discovery rate (FDR) p-values after multiple testing correction in brackets. [HW = Hardy-Weinberg equilibrium, COMT = Catechol-O-methyltransferase, NSSI = non-suicidal self-injury, total = total sample].

HW p-value: 0,45 total female male
χ2 p-value χ2 p-value χ2 p-value
rs4633
transient thought 1.532 0.465 0.041 0.98 2.044 0.36
concrete thought 1.1 0.577 1.881 0.39 1.346 0.51
NSSI 3.785 0.151 3.09 0.213 0.679 0.712
self-harm 2.519 0.284 5.15 0.076 0.256 0.88
suicide attempt 0.929 0.628 0.714 0.7 0.169 0.919
rs4680
transient thought 1.31 0.519 0.041 0.98 1.575 0.455
concrete thought 1.213 0.545 1.881 0.39 1.777 0.411
NSSI 4.047 0.132 3.09 0.213 1.863 0.394
self-harm 1.88 0.391 5.15 0.076 0.893 0.64
suicide attempt 0.502 0.778 0.714 0.7 0.015 0.993
HW p-value: 0,46 total female male
χ2 p-value χ 2 p-value χ 2 p-value
rs737865
transient thought 0.248 0.883 0.357 0.836 0.113 0.945
concrete thought 5.17 0.075 2.687 0.26 2.639 0.267
NSSI 1.422 0.491 2.956 0.228 0.267 0.875
self-harm 0.431 0.806 2.187 0.335 4.72 0.94
suicide attempt 6.08 0.048 1.12 0.57 10.1 0.006 [0.030]
HW p-value: 0,8 total female male
χ 2 p-value χ 2 p-value χ 2 p-value
rs6269
transient thought 0.965 0.617 1.034 0.596 2.391 0.302
concrete thought 8.085 0.018 [0.09] 5.549 0.062 2.943 0.23
NSSI 2.635 0.268 1.948 0.378 0.392 0.822
self-harm 1.986 0.37 2.218 0.33 1.599 0.45
suicide attempt 2.383 0.304 0.311 0.856 3.784 0.151
HW p-value: 0,55 total female male
χ 2 p-value χ 2 p-value χ 2 p-value
rs165599
transient thought 2.296 0.317 0.438 0.803 5.625 0.06
concrete thought 3.018 0.221 0.08 0.961 7.722 0.021 [0.1]
non-suicidal self-mutilation 3.256 0.196 0.955 0.622 2.265 0.322
self-harm 1.881 0.39 3.21 0.201 0.118 0.943
suicide attempt 1.027 0.598 0.619 0.734 2.277 0.32