Figure 3.

Examples of nodules with observer annotations and results of the proposed method, where the segmented vessels are indicated in blue and the segmented solid cores in red. Top: Nodules in which there is a high method-observer agreement for vessel and/or solid core segmentation. Bottom: Nodule in which there is a low method-observer agreement for vessel and/or solid core segmentation. Each column represents a separate nodule in which the first row indicates the axial slice that is considered for the evaluation. The second, third, and fourth rows show the annotations of observer 1, 2, and 3, respectively. The results of the proposed method are shown in the fifth row. All images are shown at a standard lung window level (width = 1600, center = −600) with a field of view of 10 × 10 mm.