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. 2018 Jan 12;8:693. doi: 10.1038/s41598-017-17704-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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STAP1 knockdown does not sensitize cells towards prednisolone, ibrutinib or rapamycin. (a–c) The efficacy of prednisolone (a), ibrutinib (b), and rapamycin (c) was tested in Nalm6 and Kasumi-2 cells, in which STAP1 was silenced. Three days after transduction, Nalm6 and Kasumi-2 cells were exposed to a concentration range of the indicated compounds. After four days, viability was quantified using an MTS assay. Values represent mean ± SEM of four independent experiments of Nalm6 and three independent experiments of Kasumi-2.