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. 2018 Jan 12;8:606. doi: 10.1038/s41598-017-18739-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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miR-143-3p downregulation in OS tissues and cell lines is associated with poor prognosis. (A) The miR-143-3p expression is significantly decreased in OS tissues. (B) miR-143-3p expression relative to adjacent normal tissues for 20 patients. (C) The miR-143-3p expression in MG-63 and 143B cell lines are significantly lower compare to hFOB 1.19 cell line determined by qRT-PCR. (D) Kaplan-Meier curves were performed for survival in all 33 patients.