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. 2018 Jan 8;4:241. doi: 10.3389/fmed.2017.00241

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Copyright © 2018 Reiding, Vreeker, Bondt, Bladergroen, Hazes, van der Burgt, Wuhrer and Dolhain.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The relation between changing rheumatoid arthritis disease activity [ΔDAS28(3)-CRP] and changing glycosylation. Distinction is made between the timeframes to assess responder status (the change between first and third trimester; top row) and flare status (the change between third trimester and 12 weeks postpartum; bottom row). ΔA2S0G, the change in galactosylation per antenna of diantennary non-sialylated species; ΔA2FS0G, the change in galactosylation of diantennary fucosylated non-sialylated species; ΔA3FGS, the change in sialylation per galactose of triantennary fucosylated species. The significance of the models (p) arrives from linear regression, the correlation coefficients (r) from Pearson correlation.