Fig. 5.

Effect of ginsenoside Rg₃ on zymosan-induced peritonitis in mice. C57BL/6 mice were treated with zymosan (30 mg/kg, i.p.), and 12 h later treated with vehicle (n = 5) or ginsenoside Rg₃ (1 mg/kg or 5 mg/kg; n = 5) by intraperitoneal injection. After a further 12 h, mouse peritoneal cells were collected, May–Grünwald and Giemsa stained, and counted. (A) Representative photos of peritoneal cells. (B) Total cell counts in peritoneal fluids of mice with zymosan-induced peritonitis (zymosan), and ginsenoside Rg₃ (1 mg/kg or 5 mg/kg) treated mice with zymosan-induced peritonitis (zymosan + ginsenoside Rg₃). (C) Cells counts of polymorph nuclear lymphocytes (PMNLs), mononuclear lymphocytes (MNLs), and macrophages in the peritoneal cavity fluids of zymosan or zymosan+ ginsenoside Rg₃ (1 mg/kg or 5 mg/kg) treated mice. The values shown are means ± SEs (n = 5). Statistically significant at ***p < 0.001 level versus mice in the zymosan-treated group. SE, standard error; i.p., intraperitoneally.