Fig. 3.

Time to deterioration of all prespecified PROs symptoms of interest: cough, dyspnea, and pain by mutation type (Del19 and L858R). HRs from Cox proportional hazard model stratified by race in LUX-Lung 3. p-values calculated from log-rank test. The median time to deterioration was not evaluable in some groups because there were not sufficient events at the time of analysis for the median value to be reached. CI, confidence interval; HR, hazard ratio; NE, not evaluable; PRO, patient-reported outcome