Table 3.
ALGS study population: patient-reported symptoms and impacts of itching by age group (N = 12 patients)
| Concept | Age, years | Total (N = 12) | ||||
|---|---|---|---|---|---|---|
| 3–5 (n = 1) | 6–8 (n = 1) | 9–11 (n = 3) | 12–17 (n = 4) | ≥18 (n = 3) | ||
| Symptom | ||||||
| Itching | 0 | 1 | 2 | 4 | 3 | 10 |
| Patient-reported impacts: physical | ||||||
| Skin damage | 0 | 0 | 2 | 3 | 2 | 7 |
| Blood from scratching | 0 | 0 | 0 | 1 | 0 | 1 |
| Fingernail damage | 0 | 0 | 0 | 1 | 0 | 1 |
| Patient-reported impacts: sleep | ||||||
| Difficulty falling asleep | 0 | 0 | 0 | 3 | 1 | 4 |
| Difficulty staying asleep | 0 | 0 | 2 | 1 | 0 | 3 |
| Patient-reported impacts: activities of daily living | ||||||
| Ability to concentrate | 0 | 0 | 1 | 2 | 1 | 4 |
| Sports/playing | 0 | 0 | 1 | 1 | 0 | 2 |
| Patient-reported impact: school | ||||||
| Feeling tired in school | 0 | 0 | 0 | 1 | 0 | 1 |
| Patient-reported impacts: social | ||||||
| Unwanted attention from others | 0 | 0 | 2 | 1 | 2 | 5 |
| Dating | 0 | 0 | 0 | 0 | 1 | 1 |
| Patient-reported impacts: work | ||||||
| Finding a job | 0 | 0 | 0 | 0 | 1 | 1 |
| Productivity | 0 | 0 | 0 | 0 | 1 | 1 |
| Patient-reported impacts: emotional | ||||||
| Mood changes | 0 | 0 | 1 | 3 | 2 | 6 |
| Embarrassment | 0 | 0 | 0 | 1 | 1 | 2 |
ALGS Alagille syndrome