Table 7.
Results of automatic logistic regression analyses with melancholic depression (MEL MDD) versus non-MEL MDD as dependent variable and immune biomarkers, i.e., interleukin-1α, soluble interleukin 1 receptor antagonist (sIL-1RA), sIL-2R, sIL-6R, soluble tumor necrosis factor receptor 60 kDa/80 kDa (sTNF-R1/R2), and thiobarbituric acid reactive substances (TBARS), age, gender, drug state, nicotine dependence, and marital status as explanatory variables
Dependent variables | Explanatory variables | Wald | df | p | Odds ratio | lower and upper 95% CI |
---|---|---|---|---|---|---|
MEL MDD (versus non-MEL MDD) | IL-1α sIL-6R PC1 PC2 |
9.52 11.88 2.53 5.72 |
1 1 1 1 |
0.002 0.001 0.112 0.017 |
0.40 29.27 0.68 1.98 |
0.23–0.72 4.29–199.76 0.43–1.09 1.13–3.47 |
PC1, PC2: the first two varimax-rotated PC subtracted from the drug state data