JH signaling promotes timp expression, and βftz-F1 inhibits timp expression.
A, timp expression in the fat body of the JH signaling-deficient animals at 6 h APF (left panel) and in the fat body of Kr-h1–overexpressing animals at 12 h APF (right panel). B, timp expression in the fat body of EcRDN-overexpressing and βftz-F1 RNAi animals at 12 h APF (left panel) and in the fat body of βftz-F1-overexpressing animals at 6 h APF (right panel). C, Mmps enzymatic activity in the fat body of JH signaling-deficient animals and βftz-F1-overexpressing animals at 6 h APF (upper panel) as well as in the fat body of EcRDN-overexpressing, βftz-F1 RNAi, and Kr-h1–overexpressing animals (lower panel).