Table 3.
ROC analysis for the differentiation between discogenic LBLP patients and healthy subjects
| Brain regions | Area under the curve | Cutoff point | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|
| Right CPL | 0.300 | 0.305 | 56.0 | 16.0 |
| Right Fus | 0.902 | 0.368 | 96.0 | 7.41 |
| Right ITG | 0.329 | 0.351 | 24.0 | 48.15 |
| Left ITG | 0.299 | 0.289 | 40.0 | 25.92 |
| Right aINS/fO | 0.387 | 0.378 | 52.0 | 18.52 |
| Bilateral OFC | 0.345 | 0.492 | 40.0 | 25.92 |
| Right MOG/MTG | 0.271 | 0.318 | 28.0 | 25.92 |
| Bilateral MB/BG/Thala | 0.929 | 0.372 | 88.0 | 85.18 |
| Left mPFC | 0.923 | 0.366 | 84.0 | 92.59 |
| Left ACC | 0.692 | 0.296 | 60.0 | 81.48 |
| Left MOG | 0.354 | 0.376 | 40.0 | 29.6 |
| Left IPL/PoCG | 0.904 | 0.378 | 84.0 | 92.6 |
| Right IPL | 0.883 | 0.418a | 72.0 | 92.6 |
Notes: With this cutoff point, the ALFF value of the right IPL could correctly classify 18 of the 25 discogenic LBLP patients and 25 of the 27 healthy subjects and resulted in a sensitivity of 72.0% and a specificity of 92.6%. The means of other cutoff points were similar.
Abbreviations: ALFF, amplitude of low-frequency fluctuation; ACC, anterior cingulate cortex; aINS, anterior insula; BG, basal ganglia; CPL, cerebellar posterior lobe; fO, frontal operculum; Fus, fusiform; IPL, inferior parietal lobule; ITG, inferior temporal gyrus; LBLP, low-back and leg pain; MB, midbrain; MOG, middle occipital gyrus; mPFC, medial prefrontal cortex; MTG, middle temporal gyrus; OFC, orbitofrontal cortex; PoCG, postcentral gyrus; ROC, receiver operating characteristic; Thala, thalamus.