Table 3.
Motor Behavioral Variable | Testing Timepoint (age of animals) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
2mo | 3mo | 4mo | 5mo | 6mo | ||||||
WT | Pink1 −/− | WT | Pink1 −/− | WT | Pink1 −/− | WT | Pink1 −/− | WT | Pink1 −/− | |
Hindlimb Steps | n/a | n/a | 106.84 (5.15) | 91.06 (5.29) | 85.72 (5.30) | 75.83 (5.29) | 80.88 (5.45) | 55.56 (5.29) | 59.94 (5.29) | 52.39 (5.29) |
Forelimb Steps | n/a | n/a | 128.11 (5.58) | 102.83 (5.73) | 99.06 (5.73) | 87.67 (5.73) | 88.59 (5.90) | 69.28 (5.73) | 69.44 (5.73) | 60.17 (5.73) |
Rears + Lands | n/a | n/a | 57.74 (3.10) | 53.94 (3.18) | 40.89 (3.18) | 37.83 (3.18) | 43.53 (3.27) | 34.94 (3.18) | 31.11 (3.18) | 23.44 (3.18) |
Average Turn Time | 3.30 (0.60) | 3.83 (0.60) | 3.25 (0.47) | 3.10 (0.60) | 2.24 (0.47) | 2.89 (0.48) | 2.74 (0.47) | 2.51 (0.47) | 2.60 (0.47) | 3.31 (0.47) |
Average Traverse Time | 6.26 (4.23) | 7.82 (4.23) | 7.51 (3.30) | 6.87 (3.40) | 5.66 (3.3) | 7.32 (3.30) | 6.77 (3.30) | 6.31 (3.30) | 25.81 (3.30) | 21.85 (3.3) |