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. 2018 Jan 9;8:2654. doi: 10.3389/fmicb.2017.02654

Table 4.

Quorum-repressed genes.

Locus taga Namea Annotationa Early stationary phase fold changeb
QS qteE qslA qteE qslA
PA0045 hypothetical protein −2.2 NC −2.9 −3.3
PA0047 hypothetical protein −2.3 NC −1.9 −2.3
PA0592 ksgA rRNA (adenine-N6,N6)-dimethyltransferase −1.6 NC NC −1.4
PA0944 purN phosphoribosylaminoimidazole synthetase −1.8 NC NC NC
PA1302 probable heme utilization protein precursor (hxuC) −2.1 NC NC NC
PA1303 signal peptidase −2.4 NC NC NC
PA1542 hypothetical protein −1.8 NC 1.7 1.9
PA1580 gltA citrate synthase (cisY) −1.6 NC NC NC
PA1595 hypothetical protein −1.9 NC NC NC
PA1757 thrH homoserine kinase −2.0 NC NC NC
PA1791 hypothetical protein −1.9 NC 2.1 −3.1
PA2583 probable sensor/response regulator hybrid −1.7 NC NC NC
PA2665 fhpR Transcriptional activator of P. aeruginosa flavohemoglobin, FhpR (ygaA) −1.7 NC NC NC
PA2770 hypothetical protein −1.7 NC NC 2.3
PA2780 bswR bacterial swarming regulator BswR −1.5 NC NC NC
PA2930 probable transcriptional regulator −2.4 NC NC NC
PA2950 pfm proton motive force protein, PMF −1.6 NC NC NC
PA2964 pabC 4-amino-4-deoxychorismate lyase −1.5 NC NC NC
PA2970 rpmF 50S ribosomal protein L32 −2.1 NC NC NC
PA2998 nqrB Na+-translocating NADH:ubiquinone oxidoreductase subunit Nrq2 −1.8 NC NC NC
PA3079 hypothetical protein −1.9 NC NC NC
PA3111 folC folylpolyglutamate synthetase −1.6 NC NC NC
PA3174 probable transcriptional regulator −1.9 −2.3 −2.7 3.2
PA3268 probable TonB–dependent receptor −3.4 NC NC NC
PA3284 hypothetical protein −3.3 −5.5 −7.4 −8.8
PA3362 hypothetical protein (amiS) −2.3 8.0 12.4 7.3
PA3473 hypothetical protein −1.7 NC NC NC
PA3609 potC polyamine transport protein PotC −2.0 NC NC NC
PA3820 secF secretion protein SecF −2.5 NC NC NC
PA3823 tgt queuine tRNA-ribosyltransferase −1.8 NC NC −1.8
PA3827 lptG Lipopolysaccharide export system permease protein LptG (yjgQ) −1.5 NC NC NC
PA3979 hypothetical protein −1.6 NC NC NC
PA4045 conserved hypothetical protein (btuF; yadT) −1.7 NC NC NC
PA4046 hypothetical protein −1.5 NC NC NC
PA4375 mexW Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexW −1.7 NC NC NC
PA4479 mreD rod shape-determining protein MreD −2.8 NC NC NC
PA4519 speC ornithine decarboxylase −1.8 1.9 2 3.2
PA4562 conserved hypothetical protein (mviN) −1.7 NC NC NC
PA4569 ispB octaprenyl-diphosphate synthase (cel) −1.8 NC NC −1.9
PA4628 lysP lysine-specific permease −1.7 NC NC NC
PA4630 hypothetical protein −2.0 −1.6 −2.6 −2.5
PA4672 peptidyl-tRNA hydrolase (pth) −2.1 NC NC NC
PA4757 conserved hypothetical protein (yeaS) −1.5 NC NC −1.4
PA4840 conserved hypothetical protein (yciH) −1.6 NC NC NC
PA5072 probable chemotaxis transducer −1.5 NC NC NC
PA5081 hypothetical protein −2.0 −1.8 NC −1.5
PA5117 typA regulatory protein TypA (bipA) −1.7 NC NC NC
PA5139 hypothetical protein −2.2 NC NC −3.3
PA5156 hypothetical protein −1.8 NC NC NC
PA5167 dctP DctP −3.9 NC NC NC
PA5168 dctQ DctQ −4.3 NC NC NC
PA5169 dctM DctM −4.9 NC NC NC
PA5194 hypothetical protein −1.7 NC NC NC
PA5250 conserved hypothetical protein −1.7 NC NC NC
PA5251 hypothetical protein −1.7 NC NC NC
PA5320 coaC Phosphopantothenoylcysteine synthase/(R)-4′-phospho-N-pantothenoylcysteine decarboxylase (coaB; coaBCI; dfp) −1.4 NC NC −1.3
PA5361 phoR two-component sensor PhoR −1.6 NC NC NC
PA5492 conserved hypothetical protein (ysxC; yihA) −1.9 NC NC NC
PA5560 atpB ATP synthase A chain (papD, uncB) −1.8 NC NC −2.4
a

Locus tags, gene names, and gene annotations from the Pseudomonas Genome Database (http://www.pseudomonas.com).

b

QS represents the WT vs. lasR rhlR comparison, while all anti-activator mutant comparisons are vs. the wild-type. BOLD denotes genes of the quorum-repressed regulon in early stationary phase also differentially expressed in log phase. Negative values indicate repression, positive values indicate activation. NC, no change.