Table 4.
Parameter results from linear mixed effects regression models.
| Variable | Semantic | Syntax | Lexical | Fluency | ||||
|---|---|---|---|---|---|---|---|---|
| β (SE) | 95% CI | β (SE) | 95% CI | β (SE) | 95%CI | β (SE) | 95% CI | |
| Age (centered) | -0.001 (0.01) | -0.017 to 0.015 | -0.01 (0.01) | -0.03 to 0.01 | -0.02 (0.02) | -0.06 to 0.01 | 0.01 (0.01) | -0.001 to 0.02 |
| Sex (male) | -0.09 (0.10) | -0.30 to 0.11 | -0.24 (0.13) | -0.46 to 0.08 | -0.15 (0.24) | -0.62 to 0.32 | 0.57 (0.11)∗∗∗ | 0.36 to 0.78 |
| WRAT-III standard score | -0.28 (0.22) | -0.28 to 0.14 | 0.75 (0.27)∗∗ | 0.23 to 1.3 | -2.7 (0.5)∗∗∗ | -0.3.7 to 1.8 | -0.70 (0.23) | -1.18 to -0.29 |
| ConsensusDx (eMCI) | -0.07 (0.11) | -0.28 to 0.14 | -0.19 (0.14) | -0.46 to 0.07 | 0.28 (0.23) | -0.2 to 0.72 | -0.23 (0.11)∗ | -0.41 to -0.01 |
| Age × Consensus Dx | -0.04 (0.02)∗ | -0.07 to -0.007 | — | — | — | — | -0.03 (0.02) | -0.06 to -0.001 |
SE, standard error; CI, confidence interval; ConsensusDx, consensus diagnosis of either early MCI (eMCI) or cognitively healthy(CH); WRAT-III, Wide Range Achievement Test-3, reading subtest. Items in bold indicate statistically significant effects at ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 without correction for multiple comparisons. No interactions were statistically significant at Bonferroni corrected alpha of p < 0.013.