Table 3.
Validation miRNAs.
| miRNA | Count abundance | log2FoldChange (control vs. sALS) | Increase/Decrease | ||
|---|---|---|---|---|---|
| Oasis 2.0 | Genboree | Oasis 2.0 | Genboree | Control vs. sALS | |
| miR-124-3p | 13 | 24 | 2.09 | 3.17 | Increased |
| miR-127-3p | 50 | 89 | 1.65 | 1.38 | Increased |
| miR-143-3p | 2111 | 3882 | 0.58 | 0.48 | Increased |
| miR-125b-2-3p | 1455 | 1424 | 0.58 | 0.62 | Increased |
| miR-9-5p | 93 | 164 | 1.91 | 1.64 | Increased |
| miR-27b-3p | 604 | 1047 | 0.74 | 0.62 | Increased |
| miR-486-5p | 377 | 2139 | −1.13 | −0.85 | Decreased |
| Let-7f-5p | 369 | 704 | −0.33 | −0.42 | Decreased |
| miR-16-5p | 78 | 152 | −0.76 | −0.77 | Decreased |
| miR-28-3p | 77 | 142 | −0.58 | −0.59 | Decreased |
| miR-146a-5p | 74 | 148 | −0.85 | −0.82 | Decreased |
| miR-150-5p | 48 | 95 | −1.53 | −1.39 | Decreased |
| miR-378a-3p | 33 | 73 | −0.9 | −0.95 | Decreased |
| miR-142-5p | 30 | 39 | −1.23 | −1.25 | Decreased |
| miR-92a-5p | 605 | 1190 | −0.52 | −0.54 | Decreased |
Values in blue indicate significantly differentially expressed miRNAs that were identified by Oasis 2.0 only. Values in yellow indicate significantly differentially expressed miRNAs that were identified by both Oasis 2.0 and Genboree. Results were filtered at corrected p-value < 0.05. sALS, sporadic amyotrophic lateral sclerosis.