Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Coagulation mechanism; Thrombin plays a vital role in generating cross-linked fibrin by cleaving Fib to fibrin and activating several other coagulation factors. Thrombin also modulates other important cellular activities via protease-activated receptors. Simultaneously, it will directly increase the platelet aggregation and the production of TXA2 to express adhesion molecules29.
