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. 2018 Jan 9;8:1929. doi: 10.3389/fimmu.2017.01929

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Copyright © 2018 Fu, Xin, Liu, Wang, Wang, Zhang, Wang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of platycodin D (PLD) on lipid rafts cholesterol levels. Cells were treated with PLD (5, 10, 20 µM) for 12 h. Membrane cholesterol levels were measured by gas–liquid chromatography and the results were plotted as µg cholesterol/mg protein. The values presented are the means ± SD of three independent experiments and differences between mean values were assessed by one-way ANOVA with Tukey’s multiple comparison test (^#p < 0.05 vs. control group; *p < 0.05, **p < 0.01 vs. LPS group).