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. 2018 Jan 11;6:e4259. doi: 10.7717/peerj.4259

Figure 1. Positive selection at individual codons in human gamete-recognition genes.

Figure 1

A single-population coalescent model of selection and recombination (omegaMap; Wilson & McVean, 2006) identified the same candidate sites under positive selection that were identified by a branch-site model of codon evolution (MEME; Table 1). Values of ω were estimated using the sliding window method for alignments of haplotypes from the 1000 Genomes Phase 1 data for three gamete-recognition genes, including (A) the sperm-expressed gene C4BPA, and the egg coat glycoprotein genes (B) ZP3 and (C) ZP2. Posterior probabilities of positive selection are shown for three candidate sites (see Table 1).