Table 2. Genomic organization of human gamete-recognition genes including candidate sites under selection.
Genome coordinates and gene structure are those in the UCSC genome browser. Ancestral alleles were identified by comparison to reference genes for other great apes.
| Gene | GRCh38/hg38 Coordinates | Number of exons | Number of codons | Candidate site under selection | Ancestral Allele | Derived Allele |
|---|---|---|---|---|---|---|
| C4BPA | chr1:207,113,026- 207,144,717 | 11 | 597 | rs4844573 chr1:207,131,555 C4BPA 300 | ACT Thr | ATT Ile |
| ZP3 | chr7:76,424,965- 76,442,056 | 8 | 424 | rs2906999 chr7:76,440,494 ZP3 315 | CCG Pro | TCG Ser |
| ZP2 | chr16:21,197,480- 21,211,547 | 19 | 745 | rs2075520 chr16:21,211,351 ZP2 36 | GTG Val | GGG Gly |
| ZP1 | Chr11:60,867,562- 60,875,656 | 12 | 638 | None |