Table 2. Genomic organization of human gamete-recognition genes including candidate sites under selection.
Gene | GRCh38/hg38 Coordinates | Number of exons | Number of codons | Candidate site under selection | Ancestral Allele | Derived Allele |
---|---|---|---|---|---|---|
C4BPA | chr1:207,113,026- 207,144,717 | 11 | 597 | rs4844573 chr1:207,131,555 C4BPA 300 | ACT Thr | ATT Ile |
ZP3 | chr7:76,424,965- 76,442,056 | 8 | 424 | rs2906999 chr7:76,440,494 ZP3 315 | CCG Pro | TCG Ser |
ZP2 | chr16:21,197,480- 21,211,547 | 19 | 745 | rs2075520 chr16:21,211,351 ZP2 36 | GTG Val | GGG Gly |
ZP1 | Chr11:60,867,562- 60,875,656 | 12 | 638 | None |