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. 2018 Jan 11;6:e4259. doi: 10.7717/peerj.4259

Table 2. Genomic organization of human gamete-recognition genes including candidate sites under selection.

Genome coordinates and gene structure are those in the UCSC genome browser. Ancestral alleles were identified by comparison to reference genes for other great apes.

Gene GRCh38/hg38 Coordinates Number of exons Number of codons Candidate site under selection Ancestral Allele Derived Allele
C4BPA chr1:207,113,026- 207,144,717 11 597 rs4844573 chr1:207,131,555 C4BPA 300 ACT Thr ATT Ile
ZP3 chr7:76,424,965- 76,442,056 8 424 rs2906999 chr7:76,440,494 ZP3 315 CCG Pro TCG Ser
ZP2 chr16:21,197,480- 21,211,547 19 745 rs2075520 chr16:21,211,351 ZP2 36 GTG Val GGG Gly
ZP1 Chr11:60,867,562- 60,875,656 12 638 None