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. 2018 Jan 14;24:29–42.

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Copyright © 2018 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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Chromosome 10 two-point single-variant LOD scores. Plot of the single-variant two-point heterogeneity logarithm of the odds (HLOD) scores produced by TwoPointLods for chromosome 10, which contains single nucleotide polymorphisms (SNPs) that exhibit suggestive evidence of linkage to myopia. The lines at 1.9 and 3.3 represent the respective suggestive and significant thresholds, respectively, recommended by Lander and Kruglyak. The SNPs in the age-related macular degeneration (AMD) risk locus HTRA1 are marked in blue.