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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Free Radic Biol Med. 2017 Nov 10;115:31–42. doi: 10.1016/j.freeradbiomed.2017.11.009

Figure 2. Topical OA-NO2 potentiates CHS responses.

Figure 2

(A–E) Balb/c mice were sensitized on the abdomen with (B and C) DNFB, (D) FITC, or (E) Oxazolone, as indicated, following topical OA-NO2 treatment. 5 d later mice were elicited on the ear with DNFB, FITC, or Oxazolone, following topical OA-NO2 application (or not, control). (A, D, and E) Ear thickness was measured 24–72 h following elicitation. Bars represent the mean increase in ear thickness ± SEM of 4–8 mice per group. Data are one representative of two individual experiments. (C) IL-17a mRNA levels were determined 12 and 24 h following elicitation with DNFB. Bars represent the mean ± SD of triplicates per group with samples pooled from three mice. Fold-change was determined using the relative qRT-PCR 2−ΔΔCt method. One representative of three individual experiments. * indicates a significant difference compared to DNFB alone treated group at each time point.