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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2017 Oct 12;24(2):308–313. doi: 10.1016/j.bbmt.2017.10.016

Table 3.

Factors Associated with Response

N % Response P
Diagnosis
 Lymphoid malignancy 13 38%
 Myeloid malignancy 23 48% 0.59
Disease status at DLI
 No evidence of disease 13 38%
 Evidence of disease 23 48% 0.59
CD3 donor chimerism at DLI1
 ≤27% 18 37%
 >27% 17 56% 0.25
Time from HCT to study intervention
 <100 days 21 57%
 >100 days 15 27% 0.07
DLI dose
 1×107 CD3/kg 26 54%
 3×107 CD3/kg 10 20% 0.07
Donor
 Related 17 47%
 Unrelated 19 42% 0.77
Patient age at treatment intervention*
 ≤56 years 18 61%
 >56 years 18 28% 0.04
Donor age at HCT*
 ≤45 years 17 41%
 >45 years 16 44% 0.88
ANC count at DLI (×103/μL)*
 ≤ 2.15 17 29%
 >2.15 17 59% 0.08
Lymphocyte count at DLI (×103/μL)*
 ≤0.46 16 25%
 >0.46 16 63% 0.03
Immunosuppression after DLI
 No 30 47%
 Yes 6 33% 0.55
*

Divided at median