Figure 1.

In vivo fungal biofilms. (A) Candida albicans biofilm growing on the luminal surface of a rat venous catheter for 24 h. Scanning electron microscopy reveals adherent organisms growing within in an extracellular matrix. (B) Immunohistochemistry of pulmonary tissue from an immunocompromised mouse infected with Aspergillus fumigatus and stained with an anti-galactosaminogalactan antibody. Brown indicates accumulation of galactosaminogalactan-containing biofilm matrix surrounding hyphae growing within pulmonary tissues.