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. 2018 Jan 10;11:136. doi: 10.3389/fnana.2017.00136

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Copyright © 2018 Xu, Long, Chen, Cheng, Yu, Huang, Wang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Myelin sheath of axon in control group was intact and homogeneous (A,A′,A″), mitochondria in myelinated axons were normal. Loose myelin sheath and damaged mitochondria were observed in the compression group (B,B′,B″). The numbers of mitochondria cristaes in 1 mitochondrion declined significantly after compression (C), the number of mitochondria analyzed per group was 30, sampled from 12 rats per group. MS, Myelin Sheath; Cri, Mitochondria Cristae; A, Axons. ^***P < 0.001 relative to controls.