Table 1.
Relationship between clinicopathological characteristics and prognosis of T4bN1-3M0/TxN3bM0 gastric cancer patients
| Clinicopathological characteristics |
All patients (n = 176) |
5-yr OS (%) | P value | |
| n | % | |||
| Sex | ||||
| Male | 131 | 74.4% | 17.4% | 0.702 |
| Female | 45 | 25.6% | 15.8% | |
| Age (yr) | ||||
| ≥ 60 | 68 | 38.6% | 21.8% | 0.799 |
| < 60 | 108 | 61.4% | 13.5% | |
| Tumor location | ||||
| Upper third | 43 | 24.4% | 17.7% | 0.614 |
| Middle third | 56 | 31.8% | 19.6% | |
| Lower third | 62 | 35.2% | 19.6% | |
| Total | 15 | 8.5% | 0.0% | |
| Tumor grade (differentiation) | ||||
| Moderate | 15 | 8.5% | 19.3% | 0.241 |
| Poor | 161 | 91.5% | 16.5% | |
| Lymphovascular invasion | ||||
| Yes | 139 | 79.0% | 10.3% | 0.010 |
| No | 37 | 21.0% | 30.6% | |
| No. of positive LNs | ||||
| 0 | 4 | 2.3% | 37.5% | 0.174 |
| 1-6 | 17 | 9.7% | 31.2% | |
| 7-15 | 10 | 5.7% | 0.0% | |
| ≥ 16 | 145 | 82.4% | 15.8% | |
| No. of dissected LNs | ||||
| ≥ 30 | 106 | 60.2% | 20.6% | 0.326 |
| < 30 | 70 | 39.8% | 11.6% | |
| Positive LN ratio | ||||
| ≥ 0.8 | 34 | 19.3% | 6.2% | 0.048 |
| < 0.8 | 142 | 80.7% | 20.5% | |
| Pathologic T stage1 | ||||
| T2 | 5 | 2.8% | 40.0% | 0.420 |
| T3 | 20 | 11.4% | 30.6% | |
| T4a | 102 | 58.0% | 12.6% | |
| T4b | 49 | 27.8% | 21.2% | |
| Stage1 | ||||
| IIIA | 5 | 2.8% | 40.0% | 0.237 |
| IIIB | 15 | 8.5% | 35.9% | |
| IIIC | 156 | 88.6% | 14.0% | |
1
Recorded based on the American Joint Committee on Cancer (AJCC) TNM Staging Classification for Carcinoma of the Stomach (7th edition, 2010). LN: Lymph node; OS: Overall survival.