Figure 8.

Incorporation of (18:2)₄CL improves the cardiolipin lipidome of mitochondria isolated from DHA-fed mice. Heat maps of major (A), intermediate (B), and minor (C) CL acyl chains for mice consuming a control (CON), Western diet (WD), and WD + DHA. D, monolyso-CL species in cardiac mitochondria are also shown. Data are the average ± S.E. from three independent experiments. Asterisks indicate significance from control (*, p < 0.05). Daggers indicate significance relative to WD + DHA + (18:2)₄CL (†, p < 0.05).