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. 2017 Oct 17;9(1):11–16. doi: 10.1021/acsmedchemlett.7b00360

Table 1. MBCs (μM) against S. aureus, P. aeruginosa, and E. coli under Two Different Conditions at 37 °C; 20 h of White Light Irradiation (4.83 mW/cm2) and in the Darka.

  MBC (μM)
  S. aureus
P. aeruginosa
E. coli
compd light dark light dark light dark
1(15) >50 >50 10.0 10.0 5.0 5.0
5(15) 0.8   2.5 10.0 0.5 1.2–5.0
1Lys     >100 >100 50.0 50.0
TMPyP 5.0   20.0   18.0  
5Lys 1.2   8.0 >100 0.8 25.0
a

These assays were performed in tryptic soy culture medium, with bacteria in their log phase. The minimal bactericidal concentration corresponds to the concentration of the active compound for which 99.99% of the bacteria have been killed (i.e., 4 log reduction compared to the untreated control). Four replicates were performed for each condition.