Table 1. MBCs (μM) against S. aureus, P. aeruginosa, and E. coli under Two Different Conditions at 37 °C; 20 h of White Light Irradiation (4.83 mW/cm2) and in the Darka.
MBC
(μM) |
||||||
---|---|---|---|---|---|---|
S. aureus |
P.
aeruginosa |
E. coli |
||||
compd | light | dark | light | dark | light | dark |
1(15) | >50 | >50 | 10.0 | 10.0 | 5.0 | 5.0 |
5(15) | 0.8 | 2.5 | 10.0 | 0.5 | 1.2–5.0 | |
1Lys | >100 | >100 | 50.0 | 50.0 | ||
TMPyP | 5.0 | 20.0 | 18.0 | |||
5Lys | 1.2 | 8.0 | >100 | 0.8 | 25.0 |
These assays were performed in tryptic soy culture medium, with bacteria in their log phase. The minimal bactericidal concentration corresponds to the concentration of the active compound for which 99.99% of the bacteria have been killed (i.e., 4 log reduction compared to the untreated control). Four replicates were performed for each condition.