Table 1.
Modified Newcastle-Ottawa Scale for Quality Assessment
| Legend | Description |
|---|---|
| Adequacy of the case definition | |
| + | Independent validation (1+ person or process) to ensure diagnostic accuracy |
| − | No description of independent validation process |
| Adequacy of control definition | |
| + | Explicitly states that controls have no history of mental illness |
| − | No mention of procedure to verify history of mental illness |
| Comparability of cases and controls on the basis of age | |
| + | Cases and controls are matched for age and/or analyses are adjusted for age |
| − | No description of comparability based on age |
| Comparability of cases and controls on the basis of sex | |
| + | Cases and controls are matched for sex and/or analyses are adjusted for sex |
| − | No description of comparability based on sex |
| Comparability of cases and controls on the basis of another variable (not age/sex) | |
| + | Cases and controls are matched for stated variable and/or analyses are adjusted for stated variable |
| − | No description of comparability based on stated variable |
| Medication summary | |
| + | Clear description of medication status for case group |
| − | No description of medication status for case group |
| Correction for multiple comparisons | |
| + | Clear description of process to correct for multiple comparisons in analyses |
| − | No description of process to correct for multiple comparisons in analyses |
| Sex and/or gender in title of journal article | |
| + | Sex and/or gender is mentioned in the title of the journal article |
| − | No mention of sex and/or gender in the title of the journal article |
| Sex analysis in abstract of journal article | |
| + | Sex analysis is described in the journal abstract |
| − | No description of sex analysis in abstract |
| Significance of sex finding mentioned in discussion section | |
| + | Significance of sex finding is discussed in above mentioned section |
| − | No discussion of sex finding in above mentioned section |