Table I.
Demographic data of patients with HBV-related hepatocellular carcinoma undergoing hepatectomy (n=114).
| A, Categorical variables | |
|---|---|
| Variablesa | No. (%) |
| Age, ≤65 years | 90 (78.9) |
| Sex (male) | 90 (78.9) |
| Comorbidity | |
| Diabetes mellitus (yes) | 19 (16.8) |
| Hypertension (yes) | 22 (19.3) |
| ESRDb (yes) | 1 (0.9) |
| Smoking (yes) | 21 (18.4) |
| Alcohol (yes) | 16 (14.0) |
| Child-pugh classification (A/B/C) | 108 (97.3)/3 (2.7)/0 (0) |
| Preoperative α-fetoprotein (>200 ng/ml) | 54 (47.4) |
| ICG-15 (≤10%) | 75 (66.4) |
| Tumor size (>5 cm) | 23 (20.2) |
| Tumor encapsulation (yes) | 93 (81.6) |
| Tumor rupture (yes) | 6 (5.3) |
| Vascular invasion (yes) | 29 (25.4) |
| Daughter nodules (yes) | 22 (19.3) |
| Resection margin (negative) | 113 (99.1) |
| Edmonson and steiner grade | 9(8.0)/59(52.2)/ |
| (I/II/III/IV) | 40(35.4)/5(4.4) |
| Liver cirrhosis (yes) | 58 (50.9) |
| Tumor necrosis (yes) | 56 (49.1) |
| AJCC T stage | 66(69.5)/18(18.9)/ |
| (T1/T2/T3a/T3b/T4) | 8(8.4)/1(1.1)/2(2.1) |
| AJCC N stage (N0) | 113 (99.1) |
| B, Continuous variables | |
| Variablesa | Mean ± SE |
| Age (years) | 55.7±1.09 |
| ICG-15 (%) | 9.62±1.02 |
| Preoperative α-fetoprotein (ng/ml) | 10,581.94±5,851.93 |
| Preoperative CEA (ng/ml) | 3.14±0.73 |
| Tumor size (cm) | 4.18±0.24 |
a
Only patients with available data were analyzed.
b
End-stage renal disease. CEA, carcinoembryonic antigen; HBV, hepatitis B virus; ICG-15, indocyanine green retention at 15 min; ESRD, end-stage kidney or renal disease; AJCC, American Joint Committee on Cancer; SE, standard error of the mean.