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. 2017 Nov 2;15(1):386–392. doi: 10.3892/ol.2017.7331

Figure 4.

Figure 4.

Interactions between S100A7 and miR-26b-5p. (A) S100A7 expression in 4 different kinds of cell lines. **P<0.01, ***P<0.001 vs. non-invasive cell lines, respectively; (B) S100A7 expression in ICC and mICC tumor tissues. ***P<0.001 vs. ICC tumor tissues. (C) The effects of miR-26b-5p mimic on invasive cell lines. ***P<0.001, ****P<0.0001 vs. non-sense controls. (D) The effects of pre-miR-26b-5p on invasive cell lines. ***P<0.001, ****P<0.0001 vs. non-sense controls. (E) The effects of miR-26b-5p inhibitor on RBE and HCCC-9810 cell lines. **P<0.01, ***P<0.001 vs. non-sense controls. (F) Effects of miR-26b-5p mimic and inhibitor on 3′UTR region of S100A7. NG, P>0.05; **P<0.01; ***P<0.001; all vs. non-sense control. ICC, intrahepatic cholangiocarcinoma; mICC, ICC with lymphatic metastasis; 3′UTR, 3′ untranslated region; S100A7, S100 calcium-binding protein A7; miR, microRNA; iRBE, invasive subpopulation of RBE cells; iHCCC-9810, invasive subpopulation of HCCC-9810 cells.